Temperature-Programmed Capillary Electrophoresis for Detection of DNA Point Mutations
نویسندگان
چکیده
منابع مشابه
Temperature-programmed capillary electrophoresis for detection of DNA point mutations.
A method for unambiguous determination of point mutations in genomic DNA, based on electrophoresis in thin capillaries, is reported here. The method is based on the principle of temperature gradient gel electrophoresis (TGGE), a variant of denaturing gradient gel electrophoresis (DGGE), and exploits the differential melting of mutant and wild-type PCR-amplified DNA fragments during electrophore...
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ژورنال
عنوان ژورنال: BioTechniques
سال: 1996
ISSN: 0736-6205,1940-9818
DOI: 10.2144/96215rr06